Research advancement in immunopathogenesis of myasthenia gravis
نویسندگان
چکیده
منابع مشابه
O 29: Autoimmune Myasthenia Gravis Introduction, Immunopathogenesis and Classification
Autoimmune Myasthenia Gravis (MG) is a unique disease among all autoimmune disorders in two ways. First, there are a wide range of sub-specialties involved in the diagnosis and management of MG; secondly MG is an autoimmune disorder whose autoimmunity is well established. In this paper I will cover these topics: history and epidemiology of MG followed by a brief overview on physiology of neurom...
متن کاملImmunopathogenesis in Myasthenia Gravis and Neuromyelitis Optica
Myasthenia gravis (MG) and neuromyelitis optica (NMO) are autoimmune channelopathies of the peripheral neuromuscular junction (NMJ) and central nervous system (CNS) that are mainly mediated by humoral immunity against the acetylcholine receptor (AChR) and aquaporin-4 (AQP4), respectively. The diseases share some common features, including genetic predispositions, environmental factors, the brea...
متن کاملTreatment of Myasthenia Gravis Based on Its Immunopathogenesis
The prognosis of myasthenia gravis (MG) has improved dramatically due to advances in critical-care medicine and symptomatic treatments. Its immunopathogenesis is fundamentally a T-cell-dependent autoimmune process resulting from loss of tolerance toward self-antigens in the thymus. Thymectomy is based on this immunological background. For MG patients who are inadequately controlled with suffici...
متن کاملThymectomy in Patients with Myasthenia Gravis
A case of myasthenia gravis in a 15 years old girl is pre·sented. The disease was present for 5 years before thymectomy was performed. Indications for thymectomy, preoperative preparation, anesthetic and surgical management is -discussed.
متن کاملo 29: autoimmune myasthenia gravis introduction, immunopathogenesis and classification
autoimmune myasthenia gravis (mg) is a unique disease among all autoimmune disorders in two ways. first, there are a wide range of sub-specialties involved in the diagnosis and management of mg; secondly mg is an autoimmune disorder whose autoimmunity is well established. in this paper i will cover these topics: history and epidemiology of mg followed by a brief overview on physiology of neurom...
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ژورنال
عنوان ژورنال: Neuroscience Bulletin
سال: 2010
ISSN: 1673-7067,1995-8218
DOI: 10.1007/s12264-010-0604-1